"Throw first-pitch strikes and get ahead of the hitters."
The 23-year-old Bastardo will match up against 2007 National League Cy Young Award winner Jake Peavy.
Bastardo was 3-2 with a 1.89 ERA in 11 games (seven starts) with Triple-A Lehigh Valley and Double-A Reading.
"If he gets ahead of the hitters, it will make it easier for him to follow the catcher," said Manuel. "Our catchers know the team we're playing and they know everything about them. That's a big thing, throw first-pitch strikes and try to make a good quality pitch on either side of the plate."
Manuel said that the parent club didn't see much of Bastardo in Spring Training.
"Because our rotation was pretty well set and we needed to get our guys work, we only saw Antonio three or four innings in the spring," said Manuel. "He sits around 90 to 91 mph and has good command of his slider along with his changeup and fastball."
Bastardo is taking the spot of Brett Myers on the roster. Myers was placed on the 15-day disabled list Friday and is scheduled to undergo surgery on his right hip this week. The procedure is expected to sideline Myers for 10 to 12 weeks and possibly the entire season.
As for Peavy, he will be making his sixth career start against the Phillies and first since July 22, 2007. He is 2-2 with a 3.21 ERA against Philadelphia.
PHI: LHP Antonio Bastardo (0-0, -. -- ERA)
In two starts after being promoted to Triple-A, Bastardo struck out 12 while walking just three and allowing 11 hits in 13 innings. Bastardo has walked 10 and struck out 51 this season.
Wednesday night at Arizona, Peavy pitched with a tad of tendinitis in his right ankle that seemed to nag him as he worked deeper into the game. He won his third consecutive start after four losses in as many decisions, but he was hardly his usual hard-throwing self. Peavy allowed eight hits and four runs in his 6 1/3 innings. He walked one and struck out five. Not his typical numbers. "It's just bruised up a bit in the back of my ankle," Peavy said. "It's just a little bit of an ankle sprain, but you just have to work your way through it. It was good enough to go tonight. The boys picked me up. I'll be ready to go ... Tuesday against Philadelphia." Tidbits
With Bastardo officially joining the Phillies, the club announced that outfielder John Mayberry Jr. would be optioned to Triple-A Lehigh Valley. Mayberry homered for his first Major League hit, becoming the 19th Phillie to do so. He was hitting .222 (2-for-9) with a double, homer and three RBIs. ... The current Phillies roster has combined to go 22-for-103 off Peavy over his career, hitting .223 against him. ... Ryan Howard and Raul Ibanez both hit 10 home runs in May, becoming the first Phillies duo in history to each hit 10 home runs in one month. The last pair of teammates to each hit 10 homers in a month was Dan Uggla (12) and Cody Ross (10) for the Marlins in May 2008. ... Chase Utley's 12th home run of the season Monday was the 10th of his career against the Padres, including four this year. Tickets
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Wednesday: Phillies (J.A. Happ, 3-0, 3.00) at Padres (Chris Young, 4-3, 4.45), 10:05 p.m. ET
Thursday: Phillies (Cole Hamels, 3-2, 5.21) at Dodgers (Clayton Kershaw, 3-3, 4.34), 10:10 p.m. ET
Friday: Phillies (Jamie Moyer, 4-5, 6.75) at Dodgers (Eric Milton, 2-0, 3.14), 10:10 p.m. ET
Sandy Burgin is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.