A week ago, Howard received a cortisone injection in the knee, then had an MRI exam that revealed inflammation and some cartilage tears. He has continued to play, but Manuel said the knee had been sore for the past couple of days. That, and not Howard's four-strikeout performance on Saturday, was the reason he wasn't in Sunday's lineup.
Howard did appear as a pinch-hitter in the eighth inning, bouncing into a 4-6-3 double play.
With Howard out, Kevin Frandsen started at first base, and Michael Young stayed at third. Right fielder Delmon Young, who was 5-for-15 with two home runs over his previous four games, got his first start of the year in the cleanup spot but went 0-for-4.
Andrew Simon is a reporter for MLB.com. Follow him on Twitter @HitTheCutoff. This story was not subject to the approval of Major League Baseball or its clubs.