Brown, who came into Saturday's action hitting .273 with a home run, seven doubles and 11 RBIs in 24 games since his callup, told Manuel after Friday night's 4-2 win that his knee was bothering him.
"He might be in there [Sunday]," the skipper said. "We'll see where he's at."
In mid-June, when he was still with the IronPigs, Brown strained his right knee. It's unclear if his current soreness is related to that injury.
Utility man Michael Martinez started in right field in Brown's place on Saturday. Over his two seasons in the Major Leagues, Martinez has played 11 games in center field and one in left. Saturday was his first big league game in right field, though he did play there in Spring Training, Manuel said.