They strung together four consecutive hits and scored three runs against Worley in the top of the first inning in a 5-3 victory.
Brett Gardner doubled, Francisco Cervelli singled, Robinson Cano doubled and Eric Chavez singled as the Yankees took a 3-0 lead. Worley recovered to allow seven hits and three runs with seven strikeouts in six innings.
Yankees right-hander Hiroki Kuroda had better luck, holding the Phillies to six hits and one run in 5 2/3 innings.
Phillies catcher Erik Kratz homered in the eighth.
Up next for Yankees: The Yankees will travel to Lakeland, Fla., to face the Tigers on Saturday at 1:05 p.m. ET. Right-hander Freddy Garcia is slated to pitch, making his fourth spring start and his first official start since being struck in the right hand by a ball against the Blue Jays on March 14. Right-hander Max Scherzer will get the start for Detroit. Robinson Cano, Mark Teixeira and Raul Ibanez are among the regulars also slated to make the trip. The two clubs will meet again Sunday in Tampa.
Up next for Phillies: The Phillies head south to Fort Myers to play a Red Sox split squad at 1:35 p.m. ET on Saturday, in a game that can be seen on MLB.TV. Left-hander Cole Hamels takes the mound.
Todd Zolecki is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.